منابع مشابه
Browicz or Kupffer cells?
The paper is concerned to problem of discovery of macrofage cells present in the liver sinusoid, which are recognized in the world medical literature as Kuppffer cells. On the other hand in Poland the name of professor Tadeusz Browicz is firmly connected with the cells resulting in eponymous Browicz cells. The authors are trying to determine who has priority in this respect; Karl Kupffer, a pro...
متن کاملAntimicrobial properties of Kupffer cells.
To characterize the antimicrobial activities of Kupffer cells, I harvested macrophages from livers with a technique involving perfusion with collagenase and DNase. Ninety-nine percent of glass-adherent cells had typical macrophage morphology, 99% were esterase positive, and 60% phagocytosed opsonized zymosan when challenged with four particles per macrophage. Toxoplasma gondii multiplied within...
متن کاملMononuclear Phagocytes (kupffer Cells) and Endothelial Cells
The fine structural characteristics and phagocytic properties of peroxidase-positive and peroxidase-negative cells in rat hepatic sinusoids were investigated. Cells with a positive peroxidase reaction in the endoplasmic reticulum and the nuclear envelope make up approximately 40% of cells in rat hepatic sinusoids and have abundant cytoplasm containing numerous granules and vacuoles, and occasio...
متن کاملJanus-faced Kupffer cells in tumor metastasis
Kupffer cells are the resident liver macrophages of the liver; other tissues also have resident immune cells e.g., microglia in the brain. These cells have a distinct embryonic lineage when compared with circulating myeloid cells. In both the liver and brain micro-environments activation of their resident immune cells results in the synthesis of multiple growth factors and cytokines which stimu...
متن کاملPeroxisome proliferators activate Kupffer cells in vivo.
The mechanism by which peroxisome proliferators increase cell replication and cause liver tumors in rodents remains unknown. When activated, Kupffer cells, the resident hepatic macrophages, release a variety of mitogenic stimuli that could theoretically increase cell proliferation in nearby hepatocytes. Therefore, in the present study we evaluated the effect of two potent peroxisome proliferato...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2020
ISSN: 0002-9440
DOI: 10.1016/j.ajpath.2020.08.014